| Bioactivity | Ambucetamide is an antispasmodic agent. Ambucetamide alleviates menstrual pain[1][2]. |
| Invitro | Ambucetamide (6-120 μg/mL) inhibits the responses of the human myometrium to the menstrual stimulant[1].Ambucetamide (12 μg/mL) has no definite effect on the responses of the guinea-pig uterus to vasopressin[1]. |
| In Vivo | Ambucetamide (0-30 mg/kg, jugular vein injection) decreases in the amplitude and frequency of contractions in rat-uterine[2].Ambucetamide (1-10 mg/kg, femoral vein injection) reduces the tone of the uterus and increased the amplitude of contractions in dogs[2]. Animal Model: |
| Name | Ambucetamide |
| CAS | 519-88-0 |
| Formula | C17H28N2O2 |
| Molar Mass | 292.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. V R PICKLES, et al. The effects of ambucetamide on human myometrial and other preparations, and its antagonism to the menstrual stimulant. Br J Pharmacol Chemother. 1960 Mar;15(1):128-30. [2]. J B HOEKSTRA, et al. Studies with a uterine antispasmodic, ambucetamide. J Am Pharm Assoc Am Pharm Assoc. 1957 Sep;46(9):564-8. |