Bioactivity | 6-Benzoylheteratisine is a naturally occurring antagonist of the Na+ channel activator aconitine[1]. |
Invitro | 6-Benzoylheteratisine (3 μM) decreases the amplitude of the presynaptic fiber spike at all stimulus intensities tested and shiftes the curve to the right[1].6-benzoylheteratisine is capable of inhibiting stimulus-triggered epileptiform activity recorded in CA1 stratum pyramidale[1]. |
Name | 6-Benzoylheteratisine |
CAS | 99759-48-5 |
Formula | C29H37NO6 |
Molar Mass | 495.61 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. A Ameri, et al. Interaction of the structurally related aconitum alkaloids, aconitine and 6-benzyolheteratisine, in the rat hippocampus. Eur J Pharmacol. 1999 Dec 15;386(2-3):187-94. |