PeptideDB

6-Benzoylheteratisine

CAS: 99759-48-5 F: C29H37NO6 W: 495.61

6-Benzoylheteratisine is a naturally occurring antagonist of the Na+ channel activator aconitine.
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Bioactivity 6-Benzoylheteratisine is a naturally occurring antagonist of the Na+ channel activator aconitine[1].
Invitro 6-Benzoylheteratisine (3 μM) decreases the amplitude of the presynaptic fiber spike at all stimulus intensities tested and shiftes the curve to the right[1].6-benzoylheteratisine is capable of inhibiting stimulus-triggered epileptiform activity recorded in CA1 stratum pyramidale[1].
Name 6-Benzoylheteratisine
CAS 99759-48-5
Formula C29H37NO6
Molar Mass 495.61
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reference [1]. A Ameri, et al. Interaction of the structurally related aconitum alkaloids, aconitine and 6-benzyolheteratisine, in the rat hippocampus. Eur J Pharmacol. 1999 Dec 15;386(2-3):187-94.