Bioactivity | 2-Acetamidofluorene is a potent carcinogenan. 2-Acetamidofluorene is can be used fot induction of hepatocellular carcinoma (HCC) and multiple primary tumours[1][2]. |
In Vivo | 2-Acetamidofluorene-induced HCC rat liver tissues has hepatic cell degeneration, oval cell proliferation, and inflammatory cell infiltration[1]. |
Name | 2-Acetamidofluorene |
CAS | 53-96-3 |
Formula | C15H13NO |
Molar Mass | 223.27 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tan B, et al. Anti-hepatoma effect of arsenic trioxide on experimental liver cancer induced by 2-acetamidofluorene in rats. World J Gastroenterol. 2005 Oct 14;11(38):5938-43. [2]. CAMPBELL JG. Induction of multiple primary tumours in fowls with 2-acetamidofluorene. Br J Cancer. 1955 Mar;9(1):163-9. |