CAS | 342878-90-4 |
Sequence | H-Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH (Disulfide bond) |
Sequence Single | ACFWKYCV |
Molecular Formula | C49H64N10O10S2 |
Molecular Weight | 1017.24 |
Synonyms | URP (human, mouse, rat), Urotensin IIB (human, mouse, rat), UIIB (human, mouse, rat) |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Cardiovascular System & Diseases |
Description | Urotensin II-Related Peptide (human, mouse, rat) also called URP (human, mouse, rat), Urotensin IIB (human, mouse, rat), UIIB (human, mouse, rat), showed high affinity to urotensin II receptors in human and rat (Kd = 170 pM and 91 pM). Furthermore, it produced a long lasting, hypotensive effect in anesthetized rats at 10 nmol/kg. |
References | 1. Evaluation of [99mTc/EDDA/HYNIC0]octreotide derivatives compared with [111In-DOTA0,Tyr3, Thr8]octreotide and [111In-DTPA0]octreotide: does tumor or pancreas uptake correlate with the rate of internalization? D.Storch et al., J. Nucl. Med., 46, 1561 (2005) |