| CAS | 398001-88-2 |
| Sequence | H-Ile-Val-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Gln-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Ala-Arg-Ala-Ala-Arg-Glu-Gln-Ala-Thr-Thr-Asn-Ala-Arg-Ile-Leu-Ala-Arg-Val-Gly-His-Cys-NH2 |
| Sequence Single | IVLSLDVPIGLLQILLEQARARAAREQATTNARILARVGHC-NH2 |
| Molecular Formula | C194H339N63O54S |
| Molecular Weight | 4450.28 |
| Synonyms | Stresscopin-Related Peptide (6-43)-Gly-His-Cys-NH2 (human), Ucn II (human) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Urocortin II (human) also called Stresscopin-Related Peptide (6-43)-Gly-His-Cys-NH2 (human), Ucn II (human), a new member of the CRF family of neuropeptides, binds selectively to the type 2 CRF receptor (CRF-R2), with no appreciable activity on CRF-R1. |
| References | 1. Catalytic activity of ADAM28. L.Howard et al., FEBS Lett., 498, 82 (2001) 2. Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors. T.M.Reyes et al., Proc. Natl. Acad. Sci. USA, 98, 2843 (2001) 3. Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors. T.M.Reyes et al., Proc. Natl. Acad. Sci. USA, 98, 2843 (2001) |