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(Trp7,β-Ala8)-Neurokinin A (4-10)

CAS No.: 132041-95-3

(Trp7,β-Ala8)-Neurokinin A (4-10) also called R486, MEN10295, is a potent and selective NK-3 receptor antagonist, as de
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CAS 132041-95-3
Sequence H-Asp-Ser-Phe-Trp-β-Ala-Leu-Met-NH2
Sequence Single DSFW-β-ALM-NH2
Molecular Formula C41H57N9O10S
Molecular Weight 868.02
Synonyms R486, MEN10295
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description (Trp7,β-Ala8)-Neurokinin A (4-10) also called R486, MEN10295, is a potent and selective NK-3 receptor antagonist, as demonstrated by antagonism against neurokinin B on the NK-3 receptor of the rat portal vein.
References 1.  Analogs of neurokinin A(4-10) afford protection against gastroduodenal ulcers in rats. S.Evangelista et al., Peptides, 11, 293 (1990)