| CAS | 141923-40-2 |
| Sequence | H-Ser-Phe-Leu-Leu-Arg-Asn-NH2 |
| Sequence Single | SFLLRN-NH2 |
| Molecular Formula | C34H57N11O8 |
| Molecular Weight | 747.9 |
| Synonyms | SFLLRNamide, Thrombin Receptor Activator Peptide 6 amide, PAR-1 (1-6) amide (human), Proteinase Activated Receptor 1 (1-6) amide (human), Thrombin Receptor (1-6) amide (human), Coagulation Factor II Receptor (1-6) amide (human), SFLLRN-NH2 Selective Prote |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cardiovascular System & Diseases|Hematology |
| Description | TRAP-6 amide also called SFLLRNamide, Thrombin Receptor Activator Peptide 6 amide, PAR-1 (1-6) amide (human), Proteinase Activated Receptor 1 (1-6) amide (human), Thrombin Receptor (1-6) amide (human), Coagulation Factor II Receptor (1-6) amide (human), SFLLRN-NH2 Selective Protease-Activated Receptor 1 (PAR1) Agonist, is a PAR-1 thrombin receptor agonist peptide. |
| References | 1. Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function. R.M.Scarborough et al., J. Biol. Chem., 267, 13146 (1992) 2. Platelet Phosphatidylserine Exposure and Procoagulant Activity in Clotting Whole Blood--Different Effects of Collagen, TRAP and Calcium Ionophore A23187. Sofia Ramström, et al. Thromb Haemost. 2003 Jan;89(1):132-41. |