| CAS | 852805-92-6 |
| Sequence | H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Glu-Ser-Ala-Ser-Gly-Pro-Ser-Glu-Asp-Pro-Ser-Val-Asn-Phe-Leu-Lys-OH |
| Sequence Single | AAVALLPAVLLALLAPESASGPSEDPSVNFLK |
| Molecular Formula | C145H238N34O44 |
| Molecular Weight | 3161.64 |
| Synonyms | TRAF6 (cell permeable) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Alzheimer’s Disease |
| Description | TRAF6 Peptide is a cell-permeable peptide, it inhibits the interaction of TRAF6, an E3 ubiquitin ligase, with p62 (sequestosome 1). TRAF6 Peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 Peptide has good research potential in neurological diseases such as alzheimer’s disease (AD), parkinson’s, ALS, head trauma, epilepsy and stroke. |
| References | 1. Substances interfering with TRAF6-p62 interaction for inhibiting intracellular aggregate formation and methods for screening for such substances. Wooten, Marie W. Patent WO2005050170A2. |