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Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)

CAS No.: 131791-98-5

Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is an analog of the C-terminal sequence of hirudin, it acts as an an
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CAS 131791-98-5
Sequence Suc-Phe-Glu-Pro-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-D-Glu-OH
Sequence Single Suc-FEPIPEEY(SO3H)Le
Molecular Formula C64H88N10O26S
Molecular Weight 1445.52
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Cardiovascular System & Diseases|Hematology
Description Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is an analog of the C-terminal sequence of hirudin, it acts as an antithrombotic agent. It inhibits the thrombin-induced fibrin clot formation with an IC50 value of 0.087 µM.
References 1.  Human galanin: primary structure and identification of two molecular forms. M.Bersani et al., FEBS Lett., 283, 189 (1991)