| CAS | 131791-98-5 |
| Sequence | Suc-Phe-Glu-Pro-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-D-Glu-OH |
| Sequence Single | Suc-FEPIPEEY(SO3H)Le |
| Molecular Formula | C64H88N10O26S |
| Molecular Weight | 1445.52 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cardiovascular System & Diseases|Hematology |
| Description | Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is an analog of the C-terminal sequence of hirudin, it acts as an antithrombotic agent. It inhibits the thrombin-induced fibrin clot formation with an IC50 value of 0.087 µM. |
| References | 1. Human galanin: primary structure and identification of two molecular forms. M.Bersani et al., FEBS Lett., 283, 189 (1991) |