| CAS | 33507-63-0 |
| Sequence | H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 |
| Sequence Single | RPKPQQFFGLM-NH2 |
| Molecular Formula | C63H98N18O13S |
| Molecular Weight | 1347.65 |
| Synonyms | Neurokinin P |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R). |
| References | 1. Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor. Grady EF, et al. Mol Biol Cell. 1995 May;6(5):509-24. 2. MiR-34b/c-5p and the neurokinin-1 receptor regulate breast cancer cell proliferation and apoptosis. Zhang L, et al. Cell Prolif. 2018 Oct 17:e12527. |