CAS | 53749-61-4 |
Sequence | H-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 |
Sequence Single | PKPQQFFGLM-NH2 |
Molecular Formula | C57H86N14O12S |
Molecular Weight | 1191.46 |
Synonyms | Deca-Substance P |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Description | Substance P (2-11) also called Deca-Substance P, is a substance P (SP) fragment peptide. Substance P (2-11) has contracting activities on guinea pig ileum. Substance P (2-11) inhibits the permeation of 3H SP in BBMEC monolayers. |
References | 1. Immunological aspects of secretin, substance P, and VIP. Yanaihara N, et al. Gastroenterology. 1977 Apr;72(4 Pt.2):803-10. 2. Characteristics of substance P transport across the blood-brain barrier. Chappa AK, et al. Pharm Res. 2006 Jun;23(6):1201-8. |