| CAS | 882157-88-2 |
| Sequence | H-Ser-Thr-Ser-Gln-Lys-Ser-Ile-Val-Ala-Tyr-Thr-Met-OH |
| Sequence Single | STSQKSIVAYTM |
| Molecular Formula | C56H94N14O20S |
| Molecular Weight | 1315.5 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | SP 10 is a peptide originally derived from SARS-CoV Spike (S) protein, it corresponds to amino acid residues 668 to 679. SP 10 is a highly potent inhibitor of SARS-CoV S protein and ACE2 interaction (IC50 = 1.88 nM in biochemical assay). SP 10 inhibits interaction of SARS-CoV S protein and Vero E6 cells in vitro. |
| References | 1. Design and biological activities of novel inhibitory peptides for SARS-CoV spike protein and angiotensin-converting enzyme 2 interaction. Ho et al (2006). Antiviral Res. 69 70 PMID: 16337697 |