| CAS | 1236955-25-1 |
| Sequence | H-Ser-Val-Asp-Gln-Asp-Leu-Gly-Pro-Glu-Val-Pro-Pro-Glu-Asn-Val-Leu-Gly-Ala-Leu-Leu-Arg-Val-OH |
| Sequence Single | SVDQDLGPEVPPENVLGALLRV |
| Molecular Formula | C102H169N27O34 |
| Molecular Weight | 2317.62 |
| Synonyms | pro-SAAS (221-242) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | PEN (mouse) is a endogenous peptide GPR83 agonist. PEN (mouse) is a proSAAS-derived neuropeptide. PEN (mouse) activates phospholipase C (PLC)-mediated signaling cascade in mouse hypothalamus. |
| References | 1. Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Gomes et al (2016). Sci.Signal. 9 ra43 PMID: 27117253 2. Neuropeptide PEN and its receptor GPR83: distribution, signaling, and regulation. Mack et al (2019). ACS Chem.Neurosci. 10 1884 PMID: 30726666 |