| CAS | 1315378-73-4 |
| Sequence | H-Tyr-Lys-Lys-Thr-Glu-Ala-Val-OH (Lactam bridge:Lys3-Glu5) |
| Sequence Single | YKKTEAV (Lactam bridge:Lys3-Glu5) |
| Molecular Formula | C38H61N9O11 |
| Molecular Weight | 819.95 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | PDZ1 Domain inhibitor peptide is a novel cyclic peptide that disrupts interaction between GluK2 (formerlyy GluR6) and the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide competes with the C-terminus of GluK2 for binding to the PDZ1 domain of PSD-95. PDZ1 Domain inhibitor peptide inhibits clustering of kainate receptors. |
| References | 1. Targeting specific PDZ domains of PSD-95: structural basis for enhanced affinity and enzymatic stability of a cyclic peptide. Piserchio et al (2004). Chem.Biol. 11 469 PMID: 15123241 |
PDZ1 Domain inhibitor peptide
CAS No.: 1315378-73-4
PDZ1 Domain inhibitor peptide is a novel cyclic peptide that disrupts interaction between GluK2 (formerlyy GluR6) and th
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