| CAS | 245443-51-0 |
| Sequence | H-Gly-Tyr-Pro-Gly-Gln-Val-NH2 |
| Sequence Single | GYPGQV-NH2 |
| Molecular Formula | C28H42N8O8 |
| Molecular Weight | 618.69 |
| Synonyms | GYPGQVamide, Proteinase Activated Receptor 4 (1-6) amide (human), Coagulation Factor II Receptor-Like 3 (1-6) amide (human), Thrombin Receptor-Like 3 (1-6) amide (human), GYPGQV-NH2 Selective Protease-Activated Receptor 4 (PAR4) Agonist |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Hematology |
| Description | PAR-4 (1-6) amide (human) also called GYPGQVamide, Proteinase Activated Receptor 4 (1-6) amide (human), Coagulation Factor II Receptor-Like 3 (1-6) amide (human), Thrombin Receptor-Like 3 (1-6) amide (human), GYPGQV-NH2 Selective Protease-Activated Receptor 4 (PAR4) Agonist, is the tethered ligand sequence of human PAR-4. |
| References | 1. Cloning and sequence analysis of cDNA encoding a precursor for rat brain natriuretic peptide. M.Kojima et al., Biochem. Biophys. Res. Commun., 159, 1420 (1989) 2. Proteinase-activated receptor-1 (PAR-1) activation contracts the isolated human renal artery in vitro. M.Tognetto et al., Br. J. Pharmacol., 139, 21 (2003) 3. Proteinase-activated receptor 4 (PAR4): action of PAR4-activating peptides in vascular and gastric tissue and lack of cross-reactivity with PAR1 and PAR2. M.D.Hollenberg et al., Can. J. Physiol. Pharmacol., 77, 458 (1999) |