| CAS | 942413-05-0 |
| Sequence | H-Val-Lys-Gly-Ile-Leu-Ser-NH2 |
| Sequence Single | VKGILS-NH2 |
| Molecular Formula | C28H54N8O7 |
| Molecular Weight | 614.79 |
| Synonyms | VKGILSamide, retro-PAR-2 (1-6) amide (human), Proteinase Activated Receptor 2 (6-1) amide (human), Thrombin Receptor-Like 1 (6-1) amide (human), Coagulation Factor II Receptor-Like 1 (6-1) amide (human), retro-SLIGKVamide |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Hematology |
| Description | PAR-2 (6-1) amide (human) also called VKGILSamide, retro-PAR-2 (1-6) amide (human), Proteinase Activated Receptor 2 (6-1) amide (human), Thrombin Receptor-Like 1 (6-1) amide (human), Coagulation Factor II Receptor-Like 1 (6-1) amide (human), retro-SLIGKVamide, is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). PAR-2 (6-1) amide (human) has no effect on DNA synthesis in cells. |
| References | 1. Evidence That PAR-1 and PAR-2 Mediate Prostanoid-Dependent Contraction in Isolated Guinea-Pig Gallbladder. M Tognetto, et al. Br J Pharmacol. 2000 Oct;131(4):689-94. 2. Proinflammatory and Proliferative Responses of Human Proximal Tubule Cells to PAR-2 Activation. David A Vesey, et al. Am J Physiol Renal Physiol. 2007 Nov;293(5):F1441-9. |