| CAS | 164081-25-8 |
| Sequence | H-Ser-Leu-Ile-Gly-Arg-Leu-OH |
| Sequence Single | SLIGRL |
| Molecular Formula | C29H55N9O8 |
| Molecular Weight | 657.81 |
| Synonyms | SLIGRL, Proteinase Activated Receptor 2 (1-6) (mouse, rat), Thrombin Receptor-Like 1 (1-6) (mouse, rat), Coagulation Factor II Receptor-Like 1 (1-6) (mouse, rat) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Hematology |
| Description | PAR-2 (1-6) (mouse, rat) also called SLIGRL, Proteinase Activated Receptor 2 (1-6) (mouse, rat), Thrombin Receptor-Like 1 (1-6) (mouse, rat), Coagulation Factor II Receptor-Like 1 (1-6) (mouse, rat), is the tethered ligand sequence of mouse PAR-2, which like the thrombin receptor is a protease-activated receptor present in keratinocytes. PAR-2 (1-6) (mouse, rat) was found to be equipotent with SFLLRN in activating keratinocyte inositolphospholipid hydrolysis and calcium mobilization. |
| References | 1. Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation. S.Shoma et al., Infect. Immun., 76, 1547 (2008) |