| CAS | 1374694-00-4 |
| Sequence | H-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2 |
| Sequence Single | LYELLHGAGNHAAGILTL-NH2 |
| Molecular Formula | C85H136N24O23 |
| Molecular Weight | 1862.16 |
| Synonyms | Hypocretin-1 (16-33) (Human, Mouse Rat) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Obesity Research |
| Description | Orexin A (16-33) also called Hypocretin-1 (16-33) (Human, Mouse Rat), lacks the disulfide bridges of orexin A, but retains a part of the activity of full-length Orexin A/Orexin B. Orexin A (16-33) has been used in place of the intact neuropeptide. |
| References | 1. Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self-DNA based on CpG-specific recognition of phosphodiester DNA. C.Coch et al., J. Leukoc. Biol., 86, 663 (2009) 2. Intramolecular fluorescence resonance energy transfer (FRET) sensors of the orexin OX1 and OX2 receptors identify slow kinetics of agonist activation. T.-R.Xu et al., J. Biol. Chem., 287, 14937 (2012) |