PeptideDB

Neurotensin

CAS No.: 55508-42-4

Neurotensin (NT) is a tridecapeptide hormone, it has a wide spectrum of pharmacological effects.
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CAS 55508-42-4
Sequence Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH
Sequence Single pELYENKPRRPYIL
Molecular Formula C78H121N21O20
Molecular Weight 1672.95
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Parkinson’s Disease
Description Neurotensin (NT) is a tridecapeptide hormone, it has a wide spectrum of pharmacological effects.
References 1.  Fluorometric assay for adenosine 3’,5’-cyclic monophosphate-dependent protein kinase and phosphoprotein phosphatase activities. D.E.Wright et al., Proc. Natl. Acad. Sci. USA, 78, 6048 (1981) 2.  The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. R.Carraway and S.E.Leeman, J. Biol. Chem., 248, 6854 (1973) 3.  The amino acid sequence of a hypothalamic peptide, neurotensin. R.Carraway and S.E.Leeman, J. Biol. Chem., 250, 1907 (1975) 4.  The role of neurotensin in central nervous system pathophysiology: what is the evidence? F.St-Gelais et al., J. Psychiatry Neurosci., 31, 229 (2006) 5.  Neurotensin and its receptors in the control of glucose homeostasis. J.Mazella et al., Front. Endocrinol., 3, 143 (2012) 6.  Neurotensin: role in psychiatric and neurological diseases. R.Caceda et al., Peptides, 27, 2385 (2006) 7.  The synthesis of neurotensin. R.Carraway and S.E.Leeman, J. Biol. Chem., 250, 1912 (1975)