| CAS | 103131-69-7 |
| Sequence | H-Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu-OH |
| Sequence Single | IARRHPYFL |
| Molecular Formula | C56H85N17O11 |
| Molecular Weight | 1172.4 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cardiovascular System & Diseases|Inflammation Research |
| Description | Kinetensin is a biologically active neurotensin-related peptide, it has been obtained by pepsin treatment of human, bovine and dog plasma albumins. Its structure is similar to neurotensin and angiotensin I. Kinetensin increases vascular permeability when injected intradermally into rats and releases histamine from rat mast cells in vitro. |
| References | 1. Selective agonists for substance P and neurokinin receptors. G.Drapeau et al., Neuropeptides, 10, 43 (1987) 2. Structure of a biologically active neurotensin-related peptide obtained from pepsin-treated albumin(s). R.E.Carraway et al., J. Biol. Chem., 262, 5968 (1987) 3. The amino acid sequence of kinetensin, a novel peptide isolated from pepsin-treated human plasma: homology with human serum albumin, neurotensin and angiotensin. Biochem Biophys Res Commun. Mogard MH, et al. 1986 May 14;136(3):983-8. 4. Stimulation of histamine release by the peptide kinetensin. Sydbom A, et al. Agents Actions. 1989 Apr;27(1-2):68-71. |