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Neuromedin U-25 (porcine)

CAS No.: 98395-76-7

Neuromedin U-8 and neuromedin U-25 from porcine spinal cord are potent stimulators of rat uterus smooth muscle. Both pep
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CAS 98395-76-7
Sequence H-Phe-Lys-Val-Asp-Glu-Glu-Phe-Gln-Gly-Pro-Ile-Val-Ser-Gln-Asn-Arg-Arg-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2
Sequence Single FKVDEEFQGPIVSQNRRYFLFRPRN-NH2
Molecular Formula C144H217N43O37
Molecular Weight 3142.57
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Cardiovascular System & Diseases
Description Neuromedin U-8 and neuromedin U-25 from porcine spinal cord are potent stimulators of rat uterus smooth muscle. Both peptides have also been reported to influence blood pressure in rats and dogs.
References 1.  [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist. J.Fuhlendorff et al., Proc. Natl. Acad. Sci. USA, 87, 182 (1990) 2.  Effect of synthetic neuromedin U-8 and U-25, novel peptides identified in porcine spinal cord, on splanchnic circulation in dogs. S.Sumi et al., Life Sci., 41, 1585 (1987)