N-Me-Abz-Amyloid β/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide

CAS No.: 600728-90-3

N-Me-Abz-Amyloid β/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide also called N-Me-Abz-APP770 (708-

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CAS	600728-90-3
Sequence	N-Me-Abz-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH2
Sequence Single	N-Me-Abz-GGVVIATVK(Dnp)rrr-NH2
Molecular Formula	C70H116N26O18
Molecular Weight	1609.86
Synonyms	N-Me-Abz-APP770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide, N-Me-Abz-Amyloid β-Protein (37-44)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Application	Alzheimer’s Disease
Description	N-Me-Abz-Amyloid β/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide also called N-Me-Abz-APP770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide, N-Me-Abz-Amyloid β-Protein (37-44)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide, is a intramolecularly quenched fluorescent, presenilin-dependent substrate for assaying γ-secretase activity. The FRET substrate has been used for partial purification and characterization of γ-secretase from post-mortem human brain.

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