| CAS | 2022956-48-3 |
| Sequence | H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-NH2 |
| Sequence Single | MEVGWYRSPFSRVVHLYRNGK-NH2 |
| Molecular Formula | C118H178N36O28S |
| Molecular Weight | 2581 |
| Synonyms | MOG (35-55) amide (rat, mouse), MOG (35-55) (mouse, rat)-NH2 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Multiple Sclerosis |
| Description | Myelin Oligodendrocyte Glycoprotein (35-55) amide (rat, mouse) also called MOG (35-55) amide (rat, mouse), MOG (35-55) (mouse, rat)-NH2, is a fragment 35-55 of myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide. MOG peptide (35-55) is specific to expanded CD4+ T cells, and induces experimental autoimmune encephalomyelitis (EAE) in animal model. |
| References | 1. Poly-proline-based chiral stationary phases: a molecular dynamics study of triproline, tetraproline, pentaproline and hexaproline interfaces. M.Ashtari and N.M.Cann, J. Chromatogr. A, 1265, 70 (2012) 2. Opposing T cell responses in experimental autoimmune encephalomyelitis. Saligrama N, et al. Nature. 2019 Aug;572(7770):481-487. 3. Active Induction of Experimental Autoimmune Encephalomyelitis (EAE) with MOG35-55 in the Mouse. Giralt M, et al. Methods Mol Biol. 2018;1791:227-232. 4. Eosinophils are dispensable for development of MOG35-55-induced experimental autoimmune encephalomyelitis in mice. Ruppova K, et al. Immunol Lett. 2021 Nov;239:72-76. |