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Myelin Basic Protein (83-99) (bovine)

CAS No.: 178823-45-5

Myelin Basic Protein (83-99) (bovine) also called MBP (83-99) (bovine), is a MBP-specific T cell lines recognizing the i
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CAS 178823-45-5
Sequence H-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH
Sequence Single ENPVVHFFKNIVTPRTP
Molecular Formula C93H143N25O24
Molecular Weight 1995.31
Synonyms MBP (83-99) (bovine)
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Antigen-presenting Cells|Multiple Sclerosis
Description Myelin Basic Protein (83-99) (bovine) also called MBP (83-99) (bovine), is a MBP-specific T cell lines recognizing the immunodominant epitope. MBP (83-99) induces proliferation and IFN-γ secreting of T cells.
References 1.  Human T-cell response to myelin basic protein peptide (83-99): extensive heterogeneity in antigen recognition, function, and phenotype. Hemmer B, et al. Neurology. 2.  A double mutation of MBP(83-99) peptide induces IL-4 responses and antagonizes IFN-gamma responses. Katsara M, et al. J Neuroimmunol. 2008 Aug 30;200(1-2):77-89.