| CAS | 178823-45-5 |
| Sequence | H-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH |
| Sequence Single | ENPVVHFFKNIVTPRTP |
| Molecular Formula | C93H143N25O24 |
| Molecular Weight | 1995.31 |
| Synonyms | MBP (83-99) (bovine) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Antigen-presenting Cells|Multiple Sclerosis |
| Description | Myelin Basic Protein (83-99) (bovine) also called MBP (83-99) (bovine), is a MBP-specific T cell lines recognizing the immunodominant epitope. MBP (83-99) induces proliferation and IFN-γ secreting of T cells. |
| References | 1. Human T-cell response to myelin basic protein peptide (83-99): extensive heterogeneity in antigen recognition, function, and phenotype. Hemmer B, et al. Neurology. 2. A double mutation of MBP(83-99) peptide induces IL-4 responses and antagonizes IFN-gamma responses. Katsara M, et al. J Neuroimmunol. 2008 Aug 30;200(1-2):77-89. |