| CAS | 87173-03-3 |
| Sequence | Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ser-Ser-Asn-Ala-OH |
| Sequence Single | Pam3CSSNA |
| Molecular Formula | C67H124N6O14S |
| Molecular Weight | 1269.82 |
| Synonyms | Pam3Cys-Ser-Ser-Asn-Ala-OH, Pam3CSSNA |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Immunomodulating Agents |
| Description | Mitogenic Pentapeptide also called Pam3Cys-Ser-Ser-Asn-Ala-OH, Pam3CSSNA, is a palmitoylated pentapeptide, it represents a potent activator for monocytes/macrophages and B lymphocytes. |
| References | 1. 125I-neuropeptide Y and 125I-peptide YY bind to multiple receptor sites in rat brain. M.W.Walker and R.J.Miller, Mol. Pharmacol., 34, 779 (1988) 2. Synthesis of the mitogenic S-[2,3-bis(palmitoyloxy)propyl]-N-palmitoylpentapeptide from Escherichia coli lipoprotein. K.-H.Wiesmueller et al., Hoppe-Seyler’s Z. Physiol. Chem., 364, 593 (1983) 3. Localization of the cell activator lipopeptide in bone marrow-derived macrophages by electron energy loss spectroscopy (EELS). B.Wolf et al., Immunol. Lett., 20, 121 (1989) 4. Interaction of mitogenic bacterial lipoprotein and a synthetic analogue with mouse lymphocytes. Isolation and characterization of binding proteins. L.Biesert et al., Eur. J. Biochem., 162, 651 (1987) |