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MCH (human, mouse, rat)

CAS No.: 128315-56-0

MCH (human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are
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CAS 128315-56-0
Sequence H-Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Gln-Val-OH (Disulfide bridge between 7-16)
Sequence Single DFDMLRCMLGRVYRPCWQV (Disulfide bridge between 7-16)
Molecular Formula C105H160N30O26S4
Molecular Weight 2386.84
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description MCH (human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 and 0.1 nM at MCH1 and MCH2 receptors respectively). MCH (human, mouse, rat) increases food intake in vivo.
References 1.  Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Sailer et al (2001). Proc.Natl.Acad.Sci.USA 98 7564

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