PeptideDB

LHRH II

CAS No.: 91097-16-4

LHRH II also called LH-RH II, chicken, is one of the two forms of luteinizing hormone-releasing hormone (LHRH) the hypot
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CAS 91097-16-4
Sequence Pyr-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly-NH2
Sequence Single pEHWSHGWYPG-NH2
Molecular Formula C60H69N17O13
Molecular Weight 1236.32
Synonyms LH-RH II, chicken
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Pituitary & Hypothalamic Hormones
Description LHRH II also called LH-RH II, chicken, is one of the two forms of luteinizing hormone-releasing hormone (LHRH) the hypothalamus of the domestic hen, which are structural variants of mammalian LHRH. LH-RH II (chicken) enhances gonadotrophin release in the domestic chicken.
References 1.  Interaction of endogenous chicken gonadotrophin-releasing hormone-I and -II on chicken pituitary cells. J.A.King et al., J. Endocrinol., 117, 43 (1988) 2.  Two isoforms of gonadotropin-releasing hormone are coexpressed in neuronal cell lines. A.Chen et al., Endocrinology, 142, 830 (2001) 3.  Gonadotropin-releasing hormones I and II induce apoptosis in human granulosa cells. I.S.Hong et al., J. Clin. Endocrinol. Metab., 93, 3179 (2008) 4.  GnRH-I and GnRH-II have differential modulatory effects on human peripheral blood mononuclear cell proliferation and interleukin-2 receptor gamma-chain mRNA expression in healthy males. F.Tanriverdi et al., Clin. Exp. Immunol., 142, 103 (2005) 5.  Gonadotropin-releasing hormone II stimulates female sexual behavior in marmoset monkeys. D.K.Barnett et al., Endocrinology, 147, 615 (2006) 6.  Primary structure of three forms of gonadotropin-releasing hormone (GnRH) from the pacu brain. J.F.Powell et al., Regul. Pept., 68, 189 (1997) 7.  Primary structure of solitary form of gonadotropin-releasing hormone (GnRH) in cichlid pituitary; three forms of GnRH in brain of cichlid and pumpkinseed fish. J.F.Powell et al., Regul. Pept., 57, 43 (1995) 8.  Identification of the second gonadotropin-releasing hormone in chicken hypothalamus: evidence that gonadotropin secretion is probably controlled by two distinct gonadotropin-releasing hormones in avian species. K.Miyamoto et al., Proc. Natl. Acad. Sci. USA, 81, 3874 (1984) 9.  Gonadotropin-releasing hormones I and II induce apoptosis in human granulosa cells. I.S.Hong et al., J. Clin. Endocrinol. Metab., 93, 3179 (2008) 10.  Interaction of endogenous chicken gonadotrophin-releasing hormone-I and -II on chicken pituitary cells. J.A.King et al., J. Endocrinol., 117, 43 (1988)