PeptideDB

(Leu8,D-Trp22,Tyr25)-Somatostatin-28

CAS No.: 77909-99-0

(Leu8,D-Trp22,Tyr25)-Somatostatin-28 also called [Leu8, DTrp22, Tyr25] Somatostatin (1-28), is a somatostatin analog whi
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CAS 77909-99-0
Sequence H-Ser-Ala-Asn-Ser-Asn-Pro-Ala-Leu-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-D-Trp-Lys-Thr-Tyr-Thr-Ser-Cys-OH (Disulfide bond)
Sequence Single SANSNPALAPRERKAGCKNFFwKTYTSC
Molecular Formula C138H209N41O40S2
Molecular Weight 3146.56
Synonyms [Leu8, DTrp22, Tyr25] Somatostatin (1-28)
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Gastrointestinal Research|Pituitary & Hypothalamic Hormones
Description (Leu8,D-Trp22,Tyr25)-Somatostatin-28 also called [Leu8, DTrp22, Tyr25] Somatostatin (1-28), is a somatostatin analog which can be iodinated has been used to characterize somatostatin binding sites in rat brain and hamster insulinoma membranes.
References 1.  Relationship between receptor binding and biopotency of somatostatin-14 and somatostatin-28 in mouse pituitary tumor cells. Srikant CB, et al. Endocrinology. 1985 Jul;117(1):271-8. 2.  Somatostatin 28: effects on exocrine pancreatic secretion in conscious dogs. Susini C, et al. Gastroenterology. 1980 Oct;79(4):720-4.