Leptin (116-130) amide (mouse) Leptin and Fragments Catalog

CAS	258276-95-8
Sequence	H-Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2
Sequence Single	SCSLPQTSGLQKPES-NH2
Molecular Formula	C64H109N19O24S
Molecular Weight	1560.75
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Application	Alzheimer’s Disease\|Obesity Research
Description	Leptin (116-130) amide (mouse) is a synthetic leptin peptide fragment with the sequence of SCSLPQTSGLQKPES-NH2. It can estricts weight gain and reduces food intake in female mice lacking endogenously circulating active leptin.
References	1. In vivo effects of leptin-related synthetic peptides on body weight and food intake in female ob/ob mice: localization of leptin activity to domains between amino acid residues 106-140. Grasso et al (1997). Endocrinology 138 1413 PMID: 9075696 2. Inhibitory effects of leptin-related synthetic peptide 116-130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor. Grasso et al (1999). Diabetes 48 2204 PMID: 10535455 3. Design of a synthetic leptin agonist: effects on energy balance, glucose homeostasis and thermoregulation. Rozhavskaya et al (2000). Endocrinology 141 2501 PMID: 10875251

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