PeptideDB

LDV

CAS No.: 1155866-55-9

LDV is a α4β1 integrin (VLA-4) ligand (Kd ~ 12 nM). Non-fluorescent derivative of LDV FITC.
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CAS 1155866-55-9
Sequence N-2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl-Leu-Asp-Val-Pro-Ala-Ala-Lys-OH
Sequence Single N-2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl-Leu-DVPAAK
Molecular Formula C48H70N10O12
Molecular Weight 979.13
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description LDV is a α4β1 integrin (VLA-4) ligand (Kd ~ 12 nM). Non-fluorescent derivative of LDV FITC.
References 1.  Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation. Chigaev et al (2009). J.Biol.Chem. 284 14337 PMID: 19251697 2.  Conformational mAb as a tool for integrin ligand discovery. Ben H Njus, et al. Assay Drug Dev Technol. 2009 Oct;7(5):507-15. 3.  LDV peptidomimetics equipped with biotinylated spacer-arms: synthesis and biological evaluation on CCRF-CEM cell line. Estelle Gérard, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):586-90.