| CAS | 478507-53-8 |
| Sequence | H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2 |
| Sequence Single | YNWNSFGLRY-NH2 |
| Molecular Formula | C63H83N17O15 |
| Molecular Weight | 1318.45 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cancer Research |
| Description | Kisspeptin 10 (rat) is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin 10 (rat) is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound. |
| References | 1. Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein-coupled receptor. Stafford et al (2002). Cancer Res. 62 5399 PMID: 12359743 2. Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide. Navarro et al (2004). Endocrinology 145 4565 PMID: 15242985 3. Ameliorating effect of kisspeptin-10 on methotrexate-induced sperm damages and testicular oxidative stress in rats. Güvenç M, et al. Andrologia. 2018 Oct;50(8):e13057. |