| CAS | 128340-45-4 |
| Sequence | H-Lys-Ala-Arg-Val-Tyr-p-nitro-Phe-Glu-Ala-Nle-NH2 |
| Sequence Single | KARVY-p-nitro-FEA-Nle-NH2 |
| Molecular Formula | C52H81N15O14 |
| Molecular Weight | 1140.31 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Infectious Disease |
| Description | HIV Protease Substrate VII is a peptide with the sequence of KARVY-p-nitro-FEA-Nle-NH2, it is a ideal substrate for HIV-2 protease. This chromogenic substrate is efficiently cleaved by both the HIV-1 and HIV-2 proteases. However, its low Km for the HIV-2 protease makes it the substrate of choice - in conjunction with inhibitor screening - for this enzyme (Km = 25 µM, kcat = 15 s-1). |