| CAS | 114991-28-5 |
| Sequence | H-Arg-Ile-Gln-Arg-Gly-Pro-Gly-Arg-Ala-Phe-Val-Thr-Ile-Gly-Lys-OH |
| Sequence Single | RIQRGPGRAFVTIGK |
| Molecular Formula | C73H126N26O18 |
| Molecular Weight | 1655.97 |
| Synonyms | P18IIIB, HIV gp120 Fragment (315-329), HIV-1 env Protein gp120 (283-297) (strain BRU), R15K, HIV-1 Inhibitory Peptide |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Infectious Disease|Virology |
| Description | HIV-1 env Protein gp120 (278-292) (strains BH10, BH8, HXB2, HXB3, PV22) also called P18IIIB, HIV gp120 Fragment (315-329), HIV-1 env Protein gp120 (283-297) (strain BRU), R15K, HIV-1 Inhibitory Peptide, is derived from the V3 loop of HIV-1 IIIB gp120, it can efficiently blocked HIV-1 IIIB infection of several T-cell lines and of normal human T cells. P18IIIB also blocked syncytium formation in human cells. Moreover, P18IIIB was capable of inducing HIV-1 specific cytotoxic T lymphocyte responses that could effectively kill virus-infected cells and could thus find several therapeutic applications. |