PeptideDB

(His32,Leu34)-Neuropeptide Y (32-36)

CAS No.: 168916-68-5

(His32,Leu34)-Neuropeptide Y (32-36) is the inactive NPY carboxy-terminal pentapeptide (IC50 > 100 µM) modified by repl
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CAS 168916-68-5
Sequence H-His-Arg-Leu-Arg-Tyr-NH2
Sequence Single HRLRY-NH2
Molecular Formula C33H54N14O6
Molecular Weight 742.88
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Obesity Research
Description (His32,Leu34)-Neuropeptide Y (32-36) is the inactive NPY carboxy-terminal pentapeptide (IC50 > 100 µM) modified by replacing threonine with histidine and glutamine with leucine. The resulting peptide had a dramatically improved affinity (IC50 = 0.45 µM) for the rat brain receptor.