| CAS | 313988-89-5 |
| Sequence | H-Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Ala-Aib-Arg-Gln-Arg-Tyr-NH2 |
| Sequence Single | GPSQPTYPGDNATPEQMARYYSALRRYINMA-Aib-YQYR-NH2 |
| Molecular Formula | C183H281N57O54S2 |
| Molecular Weight | 4207.73 |
| Synonyms | (Gly1,Gln4.16,Thr6.13,Tyr7,Asp10,Asn11,Pro14,Arg26,Met30,Ala31,Aib32)-Neuropeptide Y (human, rat) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Obesity Research |
| Description | (Gly1,Ser3.22,Gln4.34,Thr6,Arg19,Tyr21,Ala23.31,Aib32)-Pancreatic Polypeptide (human) also called (Gly1,Gln4.16,Thr6.13,Tyr7,Asp10,Asn11,Pro14,Arg26,Met30,Ala31,Aib32)-Neuropeptide Y (human, rat), is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. (Gly1,Ser3.22,Gln4.34,Thr6,Arg19,Tyr21,Ala23.31,Aib32)-Pancreatic Polypeptide (human) induces a high amount of food intake. |
| References | 1. The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats. C Cabrele , et al. J Biol Chem. 2000 Nov 17;275(46):36043-8. |