| CAS | 342790-23-2 |
| Sequence | H-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bonds, air oxidized) |
| Sequence Single | ICIFCCGCCHRSKCGMCCKT |
| Molecular Formula | C85H135N27O23S9 |
| Molecular Weight | 2191.77 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Antimicrobial & Antiviral Peptides|Hematology |
| Description | Hepcidin-20, a degradation product of hepcidin-25 found in plasma and urine, shows an increased antimicrobial activity compared to the full-length peptide, but it is not involved in iron metabolism. |
| References | 1. The Alzheimer’s disease-associated amyloid beta-protein is an antimicrobial peptide. S.Soscia et al., PLoS One, 5, e9505 (2010) 2. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. C.H.Park et al., J. Biol. Chem., 276, 7806 (2001) 3. Antimicrobial activity of human hepcidin 20 and 25 against clinically relevant bacterial strains: effect of copper and acidic pH. G.Maisetta et al., Peptides, 31, 1995 (2010) 4. Serum levels of the hepcidin-20 isoform in a large general population: the Val Borbera study. N.Campostrini et al., J. Proteomics, 76, 28 (2012) 5. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. C.H.Park et al., J. Biol. Chem., 276, 7806 (2001) |