PeptideDB

Hepcidin-1 (mouse)

CAS No.: 1676104-75-8

Two hepcidins have been found in mice, hepcidin-1, a homolog of human hepcidin-25 in serum and hepcidin-2, a pentacosape
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CAS 1676104-75-8
Sequence H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr-OH (Disulfide bonds between Cys7 and Cys23/Cys10 and Cys22/Cys11 and Cys19/Cys13 and Cys14)
Sequence Single DTNFPICIFCCKCCNNSQCGICCKT
Molecular Formula C111H169N31O35S8
Molecular Weight 2754.28
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Antimicrobial & Antiviral Peptides|Hematology
Description Two hepcidins have been found in mice, hepcidin-1, a homolog of human hepcidin-25 in serum and hepcidin-2, a pentacosapeptide with differing sequence in urine. Hepcidin-1 could be involved in murine brain iron metabolism.
References 1.  Effects of acute and chronic administration of GIP analogues on cognition, synaptic plasticity and neurogenesis in mice. E.Faivre et al., Eur. J. Pharmacol., 674, 294 (2012) 2.  Distribution of the iron-regulating protein hepcidin in the murine central nervous system. S.Zechel et al., J. Neurosci. Res., 84, 790 (2006) 3.  Role of hepcidin in murine brain iron metabolism. S.M.Wang et al., Cell. Mol. Life Sci., 67, 123 (2010)