| CAS | 17351-33-6 |
| Sequence | H-Met-Ala-Ser-OH |
| Sequence Single | MAS |
| Molecular Formula | C11H21N3O5S |
| Molecular Weight | 307.37 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Di- and Tripeptides |
| Description | H-Met-Ala-Ser-OH is a substrate for human methionine aminopeptidases 1D and 2. For the latter enzyme, Yang et al. determined the kinetic parameters Km 0.38 ± 0.03 mM and kcat 210 ± 5 min-1 at pH 7.5 and 30°C for the tripeptide MAS. |
| References | 1. beta-2-Thienyl-DL-alanine as an inhibitor of phenylalanine hydroxylase and phenylalanine intestinal transport. R.A.Wapnir and G.S.Moak, Biochem. J., 177, 347 (1979) 2. MAP1D, a novel methionine aminopeptidase family member is overexpressed in colon cancer. M.Leszczyniecka et al., Oncogene, 25, 3471 (2006) |