| CAS | 923-16-0 |
| Sequence | H-D-Ala-D-Ala-OH |
| Sequence Single | aa |
| Molecular Formula | C6H12N2O3 |
| Molecular Weight | 160.17 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cell Culture|Di- and Tripeptides |
| Description | H-D-Ala-D-Ala-OH is a substrate for B.subtilis D-aminopeptidase. H-D-Ala-D-Ala-OH constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. H-D-Ala-D-Ala-OH is catalyzed by D-Alanine-D-Alanine ligase. H-D-Ala-D-Ala-OH is a bacterial Endogenous Metabolite. |
| References | 1. Differential pulse cathodic stripping voltammetry of the copper complexes of glycyl-L-histidyl-glycine at a hanging mercury drop electrode. F.N.Ertas et al., Talanta, 40, 1481 (1993) 2. Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions. Kitamura Y, et al. Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1098-106. 3. DD-ligases as a potential target for antibiotics: past, present and future. Tytgat I, et al. Curr Med Chem. 2009;16(20):2566-80. |