| CAS | 2047-13-4 |
| Sequence | H-Arg-Phe-OH |
| Sequence Single | RF |
| Molecular Formula | C15H23N5O3 |
| Molecular Weight | 321.38 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cardiovascular System & Diseases|Di- and Tripeptides |
| Description | The dipeptide H-Arg-Phe-OH mimics the haemodynamic effects of FMRF amide. Both peptides increased blood pressure and heart rate in anaesthesized rats by central stimulation of the sympathetic nervous system, H-Arg-Phe-OH being approximately 4 fold more potent. |
| References | 1. Assay methods and standard preparations for plasmin, plasminogen and urokinase in purified systems, 1967-1968. A.J.Johnson et al., Thromb. Diath. Haemorrh., 21, 259 (1969) 2. FMRF-amide and L-Arg-L-Phe increase blood pressure and heart rate in the anaesthetised rat by central stimulation of the sympathetic nervous system. C.Thiemermann et al., Biochem. Biophys. Res. Commun., 175, 318 (1991) 3. FMRF-amide and L-Arg-L-Phe increase blood pressure and heart rate in the anaesthetised rat by central stimulation of the sympathetic nervous system. C.Thiemermann et al., Biochem. Biophys. Res. Commun., 175, 318 (1991) |