| CAS | 141636-65-9 |
| Sequence | Bz-Ala-Ala-D-Trp-Phe-D-Pro-Pro-Nle-NH2 |
| Sequence Single | Bz-AaWfPP-Nle-NH2 |
| Molecular Formula | C49H61N9O8 |
| Molecular Weight | 904.08 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | GR 94800 is a potent and selective NK2 receptor peptide antagonist, with pKB values of 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively. |
| References | 1. Highly potent and selective heptapeptide antagonists of the neurokinin NK-2 receptor. A B McElroy, et al. J Med Chem. 1992 Jul 10;35(14):2582-91. 2. An investigation of tachykinin NK2 receptor subtypes in the rat. M A Matuszek, et al. Eur J Pharmacol. 1998 Jul 3;352(1):103-9. 3. Excitatory motor innervation in the canine rectoanal region: role of changing receptor populations. Stephen D Tichenor, et al. Br J Pharmacol. 2002 Dec;137(8):1321-9. |