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BIM-23127

CAS No.: 179188-73-9

BIM-23127 is a selective neuromedin B receptor antagonist. BIM-23127 completely blocked suppression of food intake produ
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CAS 179188-73-9
Sequence H-D-2-Nal-Cys-Tyr-D-Trp-Orn-Val-Cys-2-Nal-NH2 (Disulfide bond)
Sequence Single H-D-2-Nal-CYw-Orn-VC-2-Nal-NH2
Molecular Formula C62H71N11O9S2
Molecular Weight 1178.45
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Obesity Research
Description BIM-23127 is a selective neuromedin B receptor antagonist. BIM-23127 completely blocked suppression of food intake produced by neuromedin B but not by neuromedin C. This result suggested an independent role for neuromedin B receptors in suppression of food intake by bombesin-like peptides and and demonstrated the utility of this group of antagonists for in vivo experiments.