| CAS | 68382-18-3 |
| Sequence | H-Tyr-Gly-Gly-Trp-Leu-OH |
| Sequence Single | YGGWL |
| Molecular Formula | C30H38N6O7 |
| Molecular Weight | 594.67 |
| Synonyms | (Trp4)-Leu-Enkephalin |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Opioid Research |
| Description | Gluten Exorphin B5 also called (Trp4)-Leu-Enkephalin. Among all exogenous opioid peptides reported to date and especially among the gluten exorphins A, B and C, gluten exorphin B5 shows the most potent activity. Its IC50 values were 0.05 µM and 0.017 µM in the GPI and MVD assays, respectively. |
| References | 1. Isolation of AF2 (KHEYLRFamide) from Caenorhabditis elegans: evidence for the presence of more than one FMRFamide-related peptide-encoding gene. N.J.Marks et al., Biochem. Biophys. Res. Commun., 217, 845 (1995) 2. Opioid peptides derived from wheat gluten: their isolation and characterization. S.Fukudome and M.Yoshikawa, FEBS Lett., 296, 107 (1992) 3. Opioid peptides derived from wheat gluten: their isolation and characterization. S.Fukudome and M.Yoshikawa, FEBS Lett., 296, 107 (1992) |