| CAS | 107936-65-2 |
| Sequence | H-Tyr-Pro-Gln-Pro-Gln-Pro-Phe-OH |
| Sequence Single | YPQPQPF |
| Molecular Formula | C43H57N9O11 |
| Molecular Weight | 875.98 |
| Synonyms | α/β-Gliadin (43-49), GD-7, Prolamin (43-49), Gluteomorphin |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Opioid Research |
| Description | Gliadorphin-7 also called α/β-Gliadin (43-49), GD-7, Prolamin (43-49), Gluteomorphin, is an opioid peptide which is formed during digestion of the gliadin component of the gluten protein. Elevated concentrations of gliadinoorphin-7 due to insufficient proteolysis has been associated with autism, schizophrenia, and celiac disease. Gliadorphin-7 can be used in the immunological response to α-gliadin. |
| References | 1. Synthesis and Antibiotic Activities of CRAMP, a Cathelin-related Antimicrobial Peptide and Its Fragments. J.-M.Ha et al., Bull. Korean Chem. Soc., 20, 1073 (1999) 2. Findings in normal rats following administration of gliadorphin-7 (GD-7). Z.Sun and R.Cade, Peptides, 24, 321 (2003) 3. Specific high-affinity binding sites for a synthetic gliadin heptapeptide on human peripheral blood lymphocytes. D.G.Payan et al., Life Sci., 40, 1229 (1987) |