| CAS | 307950-60-3 |
| Sequence | H-Gly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH |
| Sequence Single | GSSFLSPEHQKAQQRKESKKPPAKLQPR |
| Molecular Formula | C139H231N45O41 |
| Molecular Weight | 3188.63 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | [Des-octanoyl]-Ghrelin (rat) is a non-acylated, major circulating isoform of ghrelin that does not bind to the ghrelin receptor (GHS-R1a), nor induce growth hormone release. |
| References | 1. Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin. Bedendi et al (2003). Eur.J.Pharmacol. 476 87 PMID: 12969753 2. Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a GH secretagogue receptor. Thompson et al (2004). Endocrinology 145 234 PMID: 14551228 3. Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines. Cassoni et al (2004). Eur.J.Endocrinol. 150 173 PMID: 14763915 |