(Des-Gly10,tBu-D-Gly6,Pro-NHEt9)-LHRH LHRH, Analogs, Agonists, and Antagonists Catalog

CAS	61012-19-9
Sequence	Pyr-His-Trp-Ser-Tyr-tBu-D-Gly-Leu-Arg-Pro-NHEt
Sequence Single	Pyr-HWSY-tBu-gLRP-NHEt
Molecular Formula	C59H84N16O12
Molecular Weight	1209.42
Synonyms	Lecirelin , (D-Tle6)-Leuprolide, (D-Tle6)-Leuprorelin, 兰瑞肽
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Application	Pituitary & Hypothalamic Hormones\|Veterinary Medicine
Description	(Des-Gly10,tBu-D-Gly6,Pro-NHEt9)-LHRH also called Lecirelin , (D-Tle6)-Leuprolide, (D-Tle6)-Leuprorelin, a synthetic gonadotropin-releasing hormone (GnRH) analogue, acts as a GnRH agonist. Lecirelin is widely used for the research of bovine ovarian follicular cysts.
References	1. Synthesis and biological activity of the prodrug of class I major histocompatibility peptide GILGFVFTL activated by beta-glucuronidase. S.Rawale et al., J. Med. Chem., 45, 937 (2002) 2. Determination of purity degree and counter-ion content in lecirelin by capillary zone electrophoresis and capillary isotachophoresis. P.Sázelová et al., J. Chromatogr. B, 841, 145 (2006) 3. Renin and ovarian vascularization in cows with follicular cysts after epidural administration of a GnRH analogue. A.Rizzo et al., Anim. Reprod. Sci., 116, 226 (2009)

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