CAS | 86917-57-9 |
Sequence | H-D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2 |
Sequence Single | pQQwFwwM-NH2 |
Molecular Formula | C62H74N14O10S |
Molecular Weight | 1207.42 |
Synonyms | Gpant-1, Ptt-SP (4-11), [DPro4, DTrp7,9,10] Substance P (4-11) |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Description | (D-Pro4,D-Trp7.9.10)-Substance P (4-11) also called Gpant-1, Ptt-SP (4-11), [DPro4, DTrp7,9,10] Substance P (4-11), is a competitive antagonist at receptors for substance P, for bombesin and for cholecystokinin. |
References | 1. Effect of the tachykinin antagonist, [D-Pro4, D-Trp7,9,10] substance P-(4-11), on tachykinin- and histamine-induced inositol phosphate generation in intestinal smooth muscle. Bailey SJ, et al. Naunyn Schmiedebergs Arch Pharmacol. 1987 Mar;335(3):296-300. |