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Autocamtide-2-related inhibitory peptide, myristoylated

CAS No.: 201422-04-0

Autocamtide-2-related inhibitory peptide, myristoylated also called Myr-AIP, AIP Myristoylated, is the myristoylated Aut
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CAS 201422-04-0
Sequence Myr-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
Sequence Single Myr-KKALRRQEAVDAL
Molecular Formula C78H142N22O20
Molecular Weight 1708.12
Synonyms Myr-AIP, AIP Myristoylated
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description Autocamtide-2-related inhibitory peptide, myristoylated also called Myr-AIP, AIP Myristoylated, is the myristoylated Autocamtide-2-related inhibitory peptide. Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
References 1.  Neuroprotective effect of AIP on N-methyl-D-aspartate-induced cell death in retinal neurons. Laabich et al (2000). Brain Res.Mol.Brain Res. 85 32 PMID: 11146104 2.  Inhibition of CaMKII activity in the nucleus accumbens shell blocks the reinstatement of morphine-seeking behavior in rats. Liu et al (2012). Neurosci.Lett. 518 167 PMID: 22579819 3.  A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Ishida et al (1995). Biochem.Biophys.Res.Commun. 212 806 PMID: 7626114 4.  A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Ishida A, et al. Biochem Biophys Res Commun. 1995 Jul 26;212(3):806-12.