Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat) Natriuretic Peptides Catalog

CAS	88898-17-3
Sequence	H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bond)
Sequence Single	SLRRSSCFGGRIDRIGAQSGLGCNSFRY
Molecular Formula	C128H205N45O39S2
Molecular Weight	3062.45
Synonyms	rANF (1-28), Atrial Natriuretic Peptide (1-28), rat
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Application	Cardiovascular System & Diseases\|Regenerative Medicine
Description	Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat) also called rANF (1-28), Atrial Natriuretic Peptide (1-28), rat, is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.
References	1. A new family of endogenous "big" Met-enkephalins from bovine adrenal medulla: purification and structure of docosa- (BAM-22P) and eicosapeptide (BAM-20P) with very potent opiate activity. K.Mizuno et al., Biochem. Biophys. Res. Commun., 97, 1283 (1980) 2. Atrial natriuretic peptide inhibits endothelin-1-induced activation of mitogen-activated protein kinase in cultured rat mesangial cells. T.Sugimoto et al., Biochem. Biophys. Res. Commun., 195, 72 (1993) 3. Amino acid sequence of homologous rat atrial peptides: natriuretic activity of native and synthetic forms. N.G.Seidah et al., Proc. Natl. Acad. Sci. USA, 81, 2640 (1984) 4. Angiotensin II stimulates endothelin-1 secretion in cultured rat mesangial cells. Kohno M, et al. Kidney Int. 1992 Oct;42(4):860-6.

PeptideDB

Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat)

CAS No.: 88898-17-3