| CAS | 189064-08-2 |
| Sequence | H-Asp-Ala-Ala-Arg-Glu-Gly-Phe-Leu-Ala-Thr-Leu-Val-Val-Leu-His-Arg-Ala-Gly-Ala-Arg-OH |
| Sequence Single | DAAREGFLATLVVLHRAGAR |
| Molecular Formula | C93H155N31O26 |
| Molecular Weight | 2123.44 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | [Ala92]-p16 (84-103) is a peptide derived from the tumor suppressor protein p16; [Ala92]-p16 (84-103) inhibits cyclin-dependent kinase-4 (cdk4)/cyclin D1 (IC50 ~ 1.5 μM) and binds to cdk6. |
| References | 1. Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule. Fahraeus et al (1998). Oncogene 16 587 PMID: 9482104 |